Htt epitope peptide

$ 550.0

Quantity: 50 MG

In stock (can be backordered)

SKU: 1401023 Categories: ,

Description

Product name: Htt epitope peptide

Catalog#: 1401023

Organism:

Synonyms: huntingtin (Htt) protein,

CAS NO.:

Sequence: EKLMKAFESLKSFQ

Modifications:

M.W:1685.99

M.F.:C77H124N18O22S1

Purity: 95% by HPLC

Counter ion: Trifluoacetate

Format: Lyophilized powder

Description: Using peptide SPOT arrays, we identified the minimal binding epitope to be EKLMKAFESLKSFQ, comprising the N-terminal residues 5–18 of Htt and including the first residue of the poly-Gln stretch.  The Htt epitope peptide adopts a purely α-helical structure in the complex with αHtt-VL and is bound at the base of the complementarity-determining regions (CDRs) at the concave β-sheet that normally gives rise to the interface between the VL domain and its paired VH (variable domain Ig heavy chain) domain, while only few interactions with CDR-L1 and CDR-L3 are formed.

Uniprot ID:

 

Usage: For Scientific Research Use Only, Not for Human Use.