$ 450.0
Quantity: 50mg
In stock
Description
Product name: KAFAK
Catalog#: 1810101
Synonyms: KAFAKLAARLYRKALARQLGVAA,
Sequence: H-Lys-Ala-Phe-Ala-Lys-Leu-Ala-Ala-Arg-Leu-Tyr-Arg-Lys-Ala-Leu-Ala-Arg-Gln-Leu-Gly-Val-Ala-Ala-OH
M.W: 2487.01
M.F.: C114H196N36O26
Purity: 95%
Counter ion: Trifluoacetate
Format: Lyophilized powder
Description: Brugnano et al investigated an anti-inflammatory cell-penetrating peptide KAFAKLAARLYRKALARQLGVAA, (KAFAK), which inhibits MAPK-activated protein kinase 2 (MK2). MK2 controls the synthesis of many pro-inflammatory cytokines, including IL-1, TNF-α, and IL-6. The MK2 pathway is triggered in osteoarthritis and promotes release of enzymes that degrade cartilage.
