Kissper

Description

Product name: Kissper

Catalog#: 1804024

Synonyms:

CAS NO.:

Sequence: ISSCNGPCRDLNDCDGQLICIKGKCNDDPQVGTHICRGT

M.W: 4150.66

M.F.: C165H274N54O59S6

Purity: 95% by HPLC

Counter ion: Trifluoacetate

Format: Lyophilized powder

Description: Literature reports describe kiwi fruit as a food with significant effects on human health, including anti-oxidant and anti-inflammatory activity. Kissper is a 4 kDa peptide found in variable amounts in green kiwi fruit. It derives from the proteolytic cleavage of the precursor kiwellin, one of the most abundant protein components of this fruit. Kiwellin is a 20 kDa protein that may undergo in-vivo proteolytic processing originating kissper and KiTH, corresponding to the N- and C-terminal regions of the protein, respectively. The functional characterization demonstrated that kissper is endowed with pH-dependent and voltage-gated pore-forming activity characterized by anion selectivity and channelling in model synthetic planar lipid membranes. The capacity of kissper to form channel-like pathways in a lipid bilayer similar to that found in intestinal cells suggests a possible influence of this food molecule on human gastrointestinal physiology.

Uniprot ID: P84527

 

Usage: For Scientific Research Use Only, Not for Human Use.