Kyotorphin

Description

Product name: Kyotorphin

Catalog#: 1801005

Synonyms: L-Tyrosyl-L-arginine, Kiotorphin, KTP,

Sequence: Tyr-Arg

CAS NO.: 70904-56-2

M.W: 337.37

M.F.: C15H23N5O4

Purity: 95% by HPLC

Counter ion: Acetate

Format: Lyophilized powder

Description: Kyotorphin (KTP) is an endogenous analgesic dipeptide (Tyr-Arg) for which there is evidence of eventual neuroprotective and neuromodulatory properties.  Kyotorphin (KTP) is a dipeptide (Tyr-Arg) with endogenous analgesic properties, first described by Takagi et al. (1979), isolated from bovine brain. It was subsequently isolated from other sources, including the brains of mice and rats (Ueda et al., 1980), guinea pig, rabbits, and squirrels (Ignat’ev et al., 1998) and detected in the CSF in humans (Nishimura et al., 1991). Despite being about fourfold more analgesic than endogenous opioids (Shiomi et al., 1981a), KTP effect is only induced after direct injection in the brain. This limited capacity to cross the blood-brain barrier prevents its pharmacological applications.

Compound ID: 23804

 

Usage: For Scientific Research Use Only, Not for Human Use.