Nej1 (331–334)

$ 400.0

Quantity: 50 MG

Available on backorder


Product name: Nej1 (331–334)

Catalog#: 1809008

Synonyms: nuclear localization signal (NLS) , hydrophobic patch,


Sequence: KKRK



Purity: 95% by HPLC

Counter ion: Trifluoacetate

Format: Lyophilized powder

Description: Nej1 is an essential factor in the non-homologous end-joining (NHEJ) pathway and interacts with the DNA ligase complex, Lif1-Dnl4, through interactions with Lif1. We have mapped K331-V338 in the C-terminal region of Nej1 to be critical for its functionality during repair. Truncation and alanine scanning mutagenesis have been used to identify a motif in Nej1, KKRK (331–334), which is important for both nuclear targeting and NHEJ repair after localization.

Uniprot ID:


Usage: For Scientific Research Use Only, Not for Human Use.