Neuromedin U-25

$ 550.0

Quantity: 10 MG

In stock

SKU: 1289005 Categories: ,

Description

Product name: Neuromedin U-25

Catalog#: 1289005

Organism: Porcine

Synonyms: Neuromedin U (NmU), Neuromedin U-25 porcine, Nmu-25, Neuromedin U-25 (porcine), Neuromedin U-25 porcine,FKVDEEFQGPIVSQNRRYFLFRPRN-amide,

CAS NO.: 98395-76-7

Sequence: Phe-Lys-Val-Asp-Glu-Glu-Phe-Gln-Gly-Pro-Ile-Val-Ser-Gln-Asn-Arg-Arg-Tyr-Phe-Leu-Phe-Arg-Pro-Arg-Asn-NH2

Modifications: C-terminal amide

M.W: 3142.58

M.F.: C144H217N43O37

Purity: 95%

Counter ion: Trifluoacetate

Format: Lyophilized powder

Description: Neuromedin U (NmU) belongs to the neuromedin family, comprising a series of neuropeptides involved in the gut-brain axis and including neuromedins B and C (bombesin-like), K (neurokinin B), L (neurokinin A or neurotensin), N, S, and U.Neuromedin U (NMU) are bioactive peptides with a common C-terminal heptapeptide sequence (FLFRPRN-amide) among mammals, which is responsible for receptor activation, namely NMU receptor types 1 (NMUR1) and 2 (NMUR2). NmU as a candidate drug response biomarker for HER2-overexpressing cancers and as a candidate therapeutic target to limit metastatic progression and improve the efficacy of HER-targeted drugs.

Uniprot ID: P48645

Compound ID: 16136617

 

Usage: For Scientific Research Use Only, Not for Human Use.