Product name: Poly-L-lysine (PLL)
Molecular Weight: >70k
Format: Hygroscopic, yellow to brown solid
Description: Poly-L-lysine (PLL) of extracellular matrix proteins is a small natural homopolymer of the essential amino acid L-lysine that is used to coat culture substrates. PLL functions as an attachment factor that enhances cell adherence due to its strong affinity for proteins and electrostatic interactions between the positive charges on the PLL molecule and the negative charges on the cell membrane. Synthetic polymers of LL, termed poly-L-lysine (PLL), are the homopolymers composed of a few to hundreds of LL monomers. PLL exhibits a number of biological properties such as anti-viral, anti-bacterial, and anti-tumor activities. In addition, PLL enhances the cellular uptake of macromolecules. Thus, PLL has been successfully used to develop a non-viral vehicle for delivery of pharmacologically active chemical, nucleotide, and peptide drugs.
Usage: For Scientific Research Use Only, Not for Human Use.