$ 500.0
Quantity: 10Gram
In stock
Description
Product name: RAD140
Synonym: RAD-140, 2-chloro-4-[[(1R,2S)-1-[5-(4-cyanophenyl)-1,3,4-oxadiazol-2-yl]-2-hydroxypropyl]amino]-3-methylbenzonitrile,
Catalog #: 8311100
Purity: 97%
CAS No.: 1182367-47-0
Molecular Formula: C20H16ClN5O2
Molecular Weight: 393.83
Compound ID: 44200882
Description: SARM RAD140 increases cell viability against Aβ toxicity in a concentration-dependent manner. The neuroprotective effects of RAD140 are specific to apoptotic insults and dependent upon a MAPK-signaling pathway. In GDX rats treated with RAD140, RAD140 induces androgenic responses in muscle and brain, but not in reproductive tissues. Moreover, RAD140 treatment significantly protects hippocampal neurons from kainate lesion. RAD140 matched the neuroprotection observed with T against kainate, a neurotoxin known to kill hippocampal neurons via apoptosis.
