$ 4,850.0
Quantity: 1 MG
Available on backorder
Description
Product name: Blood-depressing substance I
Catalog#: 1738001
Organism: Mediterranean snakelocks sea anemone
Synonyms: BDS-1, Antihypertensive protein BDS-1,
CAS NO.:
Sequence: AAPCFCSGKPGRGDLWILRGTCPGGYGYTSNCYKWPNICCYPH
Modifications: disulfide(1-5,2-4,3-6),
M.W:
M.F.:
Purity: 95% by HPLC
Counter ion: Trifluoacetate
Format: Lyophilized powder
Description: Blood-depressing substance I (BDS-I), a 43 amino-acid peptide from sea anemone venom, is used as a specific inhibitor of Kv3-family potassium channels. We found that BDS-I acts with even higher potency to modulate specific types of voltage-dependent sodium channels.The biggest effect of BDS-I in central neurons was to enhance resurgent current in Purkinje neurons, an effect reflected in enhancement of sodium current during the repolarization phase of Purkinje neuron action potentials
Uniprot ID: P11494
Usage: For Scientific Research Use Only, Not for Human Use.
