Product name: Obestatin
CAS NO.: 1081110-72-6
Modifications: C-terminal amide,
Counter ion: Trifluoacetate
Format: Lyophilized powder
Description: Obestatin is a 23-amino-acid, amidated peptide hormone that is mainly produced in the gastrointestinal tract and is derived from the posttranslational cleavage of the same peptide precursor as ghrelin. Obestatin and ghrelin have been shown to be stored in the same secretory vesicles. Obestatin is released in a pulsatile fashion, and its diurnal pattern of release is similar to that of ghrelin and GH. It is a potential therapeutic agent for skeletal muscle injury and would benefit other myopathies related to muscle regeneration. The stimulatory effect of obestatin on ACTH was associated with an increase in pituitary CRF receptors. Obestatin also reduced the expression of pituitary somatostatin receptors (sst1/sst2), which could serve to modify its impact on hormone secretion.
Uniprot ID: Q9UBU3
Compound ID: 91826105
Usage: For Scientific Research Use Only, Not for Human Use.