$ 1,500.0
Quantity: 50 MG
Available on backorder
Description
Product name: Murein tripeptide Mtp
Catalog#: 1808159
Synonyms: Tri-DAP, L-alanyl-gamma-D-glutamyl-meso-diaminopimelate,L-alanyl-gamma-D-glutamyl-meso-diaminopimelic acid, Mpl substrate,
CAS NO.:
Sequence: L-Ala-γ-D-Glu-meso-DAP
Modifications:
M.W: C15H26N4O8
M.F.: 390.39
Purity: 95% by HPLC
Counter ion: Trifluoacetate
Format: Lyophilized powder
Description: Proinflammatory tripeptide L-Ala-γ-D-Glu-meso-DAP (Tri-DAP), a breakdown product of bacterial peptidoglycan, is known to be a natural ligand of NOD1. Accumulation of bacterial products (including Tri-DAP, fMLP, and MDP) may trigger intracellular signals that initiate intestinal inflammatory responses.The presence of Tri-DAP significantly increased phosphorylation of the peptide ULight-histone H3 (Thr-3/Ser-10) core motif ARTKQTA. Cell wall component murein tripeptide (Mtp, L-Ala-γ-D-Glu-meso-Dap), which contains a D-amino acid and a γ-peptide linkage.
Uniprot ID:
Usage: For Scientific Research Use Only, Not for Human Use.
